The following questions are only a guideto your assignment. These points should be addressed but the organisation and subheading is up to you.
1) Overview of the paper you selected.
-What is the issue addressed in the paper, is it important? Were the objectives clearly stated
– What was the study design? – What was the exposure /or intervention? -What was the main study outcome?
-What was the study population?
-What were the main findings? Are the results clearly presented?
Were the authors advise for future direction or about the study implication?
2) Appraise the internal validity
To what extent can the observed association between the exposure and outcome be attributed to non-causal explanations? Are the results likely to be affected by chance variation? -Are the results likely to be affected by biases, what kind of biases ? corroborate your arguments with details from the paper! are the results likely to be affected by confounding? If yes what are those that authors have missed? Back it up with referencing, has any interaction or sub-group analysis was conducted bring evidence from paper
3) Do you believe a causal association between exposure and outcome is plausible?
This is based on your conclusion on internal validity but also appraisal of possible causal association based on several criteria we have covered in class
4) Appraise the external validity of the finding
can the findings be applied to the source population from which the study population was derived? -Can the study results be applied to other relevant populations? Appraise the overall quality of the discussion section.
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